A synthesized peptide derived from human RPA14, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human RPA1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human RPA2, corresponding to a region within the internal amino acids.
Replication protein A 32 kDa subunitis aproteinthat in humans is encoded by theRPA2gene. As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
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