UMP/CMP kinase Antibody detects endogenous levels of total UMP/CMP kinase.
A synthesized peptide derived from human UMP/CMP kinase, corresponding to a region within N-terminal amino acids.
UMPS Antibody detects endogenous levels of total UMPS.
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants.
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