YGVYTKVSRYLDWIH
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
A synthesized peptide derived from human Activin Receptor Type IA, corresponding to a region within N-terminal amino acids.
C58H103N17O17
VLGGGSALLRSIPA
C41H74N12O12
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