6-phosphogluconate dehydrogenase (6-PGDH) is the rate-limiting enzyme of the pentose phosphate pathway, which is responsible for the production of NADPH, energy balance, growth rate, and cell viability. 6-PGDH is also associated with a variety of tumor signaling pathways, including epidermal growth factor signaling pathway and nuclear factor E2 related factor signaling pathway.<br/>
The principle of this kit is that the product generated by the 6-PGDH catalytic substrate reacts with the chromogenic agent to generate the chromogenic substance, which has the maximum absorption at 450 nm, and is calculated by measuring the OD value at 450 nm 6-PGDH enzyme activity.
