This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants.
A synthesized peptide derived from human SREBP1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human SREBP2, corresponding to a region within the internal amino acids.
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